Bulk Biological Manufacturing Facility

Centocor, Inc. Location: Cork, Ireland Square Footage: 263,000 Construction Cost: $325,000,000

Project Description:

CRB, with a local partner, was responsible for the site selection, engineering design, procurement and validation (VMP & DQ) of this state-of-the-art greenfield biological manufacturing facility located in Ireland. The plant will produce bulk biological products using 3 x 1,000L perfusion bioreactors.


The facility consists of four separate buildings totaling 24,400 m2, connected by a central spine/walkway. The four buildings include:

  • Production Building
  • Central Utilities Plan
  • Warehouse
  • Administration and Laboratory Building

Awards: ISPE Facility of the Year Award, Sustainability

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