Architecture

Advanced therapy medicinal product facilities through the eyes of a process architect

Grace Linton
Advanced therapy medicinal product (ATMP) companies are ushering in a new frontier of medicine and technologies poised to revolutionize human health. The industry is advancing at such a rapid pace that these companies are faced with vast new complexities when developing and manufacturing their products.  
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Innovation Science

Innovation Science

What is innovation science, or rather, what makes our labs capable of supporting innovation? If you look back at history, many of our famous lab inventions came about in non-conventional and even accidental ways.
10 Sustainable Lab Solutions to Implement Today

10 Sustainable Lab Solutions to Implement Today

High-performance buildings often consume massive amounts of energy, and CRB provides our clients with innovative savings solutions for their operational costs. These solutions are great for clients with new projects or renovations on the horizon, but what about clients whose current budgets don’t foresee any new design work? 
3-D Metallic Printing: “Keeping the Powder Dry, in a Digital World”

3-D Metallic Printing: “Keeping the Powder Dry, in a Digital World”

Steve Tomko
Large-scale 3-D printing is rapidly becoming a critical manufacturing technique in the electronics, aerospace and pharmaceutical industries. At CRB, we are assisting our clients in designing, permitting and/or installing these cutting-edge environments where large-scale 3-D printing utilizes flammable powders, particularly addressing aluminum and titanium products. 
Site Selection and Development Utilizing a Colored Stop/Go Rated Matrix

Site Selection and Development Utilizing a Colored Stop/Go Rated Matrix

Melissa Holshouser
How to incorporate a new process into an existing facility is a basic question that begins every project. The client usually has a preconceived idea of where a new process will go and how much space is available, but if we stop here and do what we are told, preconceived notions may drive us to a point where we find that project needs haven’t been met.
Effective Design Approaches For Academic Teaching Laboratories

Effective Design Approaches For Academic Teaching Laboratories

Dan Dozer
A Successful Way To Use Charrette Sessions With Academic Science Faculty. The teaching lab environment is one that presents its own unique set of design parameters for the architect/laboratory planner.
Five “No-cost Strategies” for your Lab Project

Five “No-cost Strategies” for your Lab Project

Laboratory owners are constantly challenged to create new research environments with limited budgets and fewer resources. In addition, consideration has to be given to the “triple bottom line” (people, planet and profit), within these strict budgetary constraints. Cost-conscious owners want facilities to meet their vision and business objectives and include flexibility, efficiency, safety and robust utility/engineering systems.
Case Study: Flexible solutions addressing operational needs are key to success in vivarium planning:

Case Study: Flexible solutions addressing operational needs are key to success in vivarium planning:

Kevin Haugh
On a recent CRB project, a research university needed to add a small rodent vivarium to an existing perinatal research center that had previously only worked with larger animals. Once funding was approved and the project team was selected, the team began the planning process by validating the program and the concept.
Start with the Foundation: Successful Design Begins with Strategic Facilities Planning

Start with the Foundation: Successful Design Begins with Strategic Facilities Planning

Rome wasn’t built in a day. Neither was it built without a foundation. Successful building design begins on the ground floor, where operations, growth, capacity and more are considered and weighed to create the detailed facility solution that is appropriately aligned around your key business objectives.  
Lab Planning Details That Matter

Lab Planning Details That Matter

Many of us have had that “AHA!” moment or said “Why didn’t I think of that?” In a lab, even the smallest of details can have a big impact on efficiency.  A good lab planner will listen to clients and researchers, and design a workspace specific to their needs.
Creating a Future Lab within an Aging Infrastructure

Creating a Future Lab within an Aging Infrastructure

Mary Carroll and Scott McNallan and Mike Morris
How do you engage a client in a way that frees his/her mind to the prospects of an open flexible lab design? How do you lead them to see the potential within an old, tired building? Many of our clients, life sciences and otherwise, have antiquated labs in antiquated buildings on campuses that have been built to their limits. 
Designing Flexibility into Small Space Renovations

Designing Flexibility into Small Space Renovations

Brian Peasley
Incorporating flexibility into any space can be challenging. With a variety of concepts, tools and equipment at a designer’s disposal, it is easy to get excited about implementing new technology. Still, every renovation project comes with its own unique set of challenges, and there is never a one-size-fits-all solution to incorporate flexibility into a project. In this blog post, I will answer some common questions about how to execute a successful renovation project with flexibility in mind.
Exploring Laboratory Capacity

Exploring Laboratory Capacity

Has anyone asked you, "What is your laboratory capacity?" In the scientific world of planning laboratories, defining capacity is not so straightforward. This makes answering the question challenging unless you have a method in place. The reality is, you have options for measuring your laboratory capacity.
Improving User Experiences & Outcomes through Design Solutions – Part 2

Improving User Experiences & Outcomes through Design Solutions – Part 2

In this two-part series, architect Chris Ertl discusses his experience with focusing a design project on the people who will occupy the space and how those user-based design choices ultimately led to better science.
Improving User Experiences & Outcomes through Design Solutions – Part 1

Improving User Experiences & Outcomes through Design Solutions – Part 1

In this two-part series, architect Chris Ertl discusses his experience with focusing a design project on the people who will occupy the space and how those user-based design choices ultimately led to better science.
Back to the Future: A Retrospective Look Forward At Lab Planning*

Back to the Future: A Retrospective Look Forward At Lab Planning*

Take a look at the picture. Would you believe that this could be the “lab of the future?”
Biocontainment: Defining The Boundaries

Biocontainment: Defining The Boundaries

Jim Daly and Marc Pelletier
The recent Ebola outbreak has caused increased media focus and attention on biocontainment. For more than three decades, CRB has worked to understand and deliver successful strategies in implementing biocontainment in biomanufacturing—practices that can be applied across research and healthcare settings.
Process Simulation and its Benefits

Process Simulation and its Benefits

Philip Lyman, PhD – Director of Process Simulation at CRB – discusses how a process model, at the right detail level and properly validated, can be an invaluable tool to compare alternatives and justify cost for manufacturing and manufacturing-related processes.