Patent expiration for blockbuster drugs, global competition, healthcare reform, mega-mergers and increased regulatory challenges are all in the midst of a global economic crisis. This is truly an extraordinary time for the pharmaceutical industry; a time where pressures to reduce the cost of their products are crucial to company survival.

Raw materials, consumables, labor, energy and initial capital investment comprise the majority of the manufacturing cost of goods for biologic and pharmaceutical drug products. The cost of raw materials, consumables and energy are cost components that have been addressed by negotiation with suppliers, high volume purchasing or more efficient use of these supplies. The initial capital investment of facilities is a component that has been escalating over the past two decades with increases in facility scale, greater complexity and regulatory concerns.

Since these complicated facilities take years to design, build and validate, the process must be initiated while products are still in development / approval stages in order to bring them to market quickly. This creates a huge business risk to drug manufacturers. Flexibility in operation is therefore tantamount to success. The paradigm that many companies have struggled with to date is that flexibility equals higher cost. Until now.

There is a new concept in biopharmaceutical facility design and construction that reduces the risk and cost of a highly flexible and adaptable facility called FutureFacility™. FutureFacility™ is flexible, easy to modify or expand and is adaptable for multiple products or changes in process platforms. FutureFacility™ provides high value as it represents a lower initial capital investment and a lower operating cost center. It is reusable and fits a model of evolving or changing business needs thereby reducing business risk.

FutureFacility™ concepts can be applied to existing facilities as well as new construction projects.

FutureFacility is a culmination of Closed Processing, Lean Manufacturing, Modular Construction, Green Design, Risk-Based Compliance and New Technologies such as Single Use Systems and Plug & Play Operations. The results are facility designs that significantly reduce facility complexity, initial capital investment, energy consumption, project schedules and cost of goods.

If you would like to know more about how CRB can help you evaluate your future facility needs, please contact us today!