WFI production insights featured in Pharma’s Almanac
Jul 8, 2019
Jarrod Wrampe, Senior Process Utility Engineer was featured in Pharma’s Almanac with an article entitled, “Membrane-Based Reverse Osmosis Systems for WFI Production.”
Water for injection (WFI) is used in the pharmaceutical industry to formulate parenteral drugs and for cleaning and other manufacturing operations. Because WFI can be incorporated into final drug formulations, the quality requirements are extremely high. Traditionally, WFI has been produced via distillation, but in the United States and Japan, pharmacopeia monographs have allowed other methods, as long as the same quality can be achieved. Following the publication of its new monograph on WFI in April 2017, the European Pharmacopoeia was brought in alignment. Reverse osmosis followed by a polishing step can be a more efficient and cost-effective solution for WFI production.
Read Jarrod’s full article to learn about the challenges and benefits of RO for WFI here.